By Rick L. Cowell
A part of the preferred secrets and techniques SERIES®, this all-new textual content offers crucial, useful info for reviewing pathology often encountered in medical occasions. prepared by way of ailment kind, it positive factors various photographs, a favored question-and-answer structure, and an in depth index that makes it effortless to discover info quick. in additional than 50 chapters, professional participants suggest key questions and supply authoritative solutions addressing the occasions that confront small animal veterinarians each day.
- Comprehensive assurance of pathology is out there through a staff of nationally famous veterinary pathology experts.
- All of crucial "need to grasp" questions and solutions are supplied within the confirmed structure of the acclaimed secrets and techniques Series.
- More than a hundred and fifty superior-quality images spotlight key concepts.
- A thorough, hugely distinctive index presents speedy and simple entry to precise topics.
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Extra resources for Veterinary Clinical Pathology Secrets
If the blood sample will not be analyzed immediately or will be sent to an outside laboratory, a blood smear should be prepared, within minutes if possible. This step will minimize the morphologic changes that occur with aging or storage of leukocytes. The air-dried blood smear should be stored at room temperature and protected from vermin and humidity until staining by the laboratory. Laboratory Evaluation of Leukocytes 35 9. How do nucleated erythrocytes affect the leukogram? Most cell-counting methodologies include nucleated red blood cells (nRBCs) as leukocytes and report a falsely increased leukocyte concentration.
Metamyelocytes are the granulocytic precursors of band neutrophils and occur infrequently in blood as part of a left shift. An indented or kidney-shaped nucleus distinguishes metamyelocytes from band neutrophils. The nuclear chromatin is less condensed and the cytoplasm more basophilic in metamyelocytes than in band and segmented neutrophils. 15. Why is a ﬁbrinogen test included on the complete blood count of some animals? Horses and ruminants often develop inflammatory disease without a signiﬁcant change in the leukogram.
The neutropenia is an acute but transient change often followed by neutrophilia, since endotoxin causes release of neutrophils from the marrow storage pool. 18. Why does severe neutropenia occur with parvoviral infection? Canine and feline parvoviruses target cells with a high mitotic rate, including hematopoietic precursors. The blood and marrow pools of segmented neutrophils are quickly depleted because of the short half-life of neutrophils and the lack of replenishment by impaired granulopoiesis.