By Susan M. North, Tania A Banks

A hugely sensible advisor appropriate for in-clinic reference, Small Animal Oncology has been designed for optimum ease of use and accessibility of knowledge. while giving transparent and updated briefing for the busy practitioner, it is also a invaluable source to the scholar with a distinct curiosity in oncology. This creation provides an summary of melanoma biology and explains the foundations of obtainable treatments. there's modern dialogue on new and constructing concepts and coverings, and advice on whilst those are indicated. The booklet covers all universal, such a lot much less universal and a few infrequent facets of small animal oncology.

  • accompanying Evolve web site contains over 20 medical situations to aim your knowledge
  • all-round sensible, necessary, each day crucial consultant to small animal oncology
  • schematic method supplies easy access to details should you want it
  • explains biology and the elemental rules in addition to indicating therapy options

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Additional resources for Small Animal Oncology: An Introduction

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G. in the management of incompletely resected mast cell tumours and soft tissue sarcomas. g. 2A,B; see Chapter 22). Adjunctive therapy for incompletely resected tumours Adjunctive therapy is the most common application of radiotherapy in veterinary medicine. 2C). This means that the tumours are predominantly located on the distal extremities or facial area. See the relevant chapters for a more in-depth discussion. 2D). g. mammary or prostatic tumours. g. 3). In many cases it is the only treatment modality for large inoperable brain tumours and for patients with granulomatous meningoencephalomyelitis (GME) that is non-responsive to medical management.

In: Tannock IF, Hill RP (eds) The Basic Science of Oncology, 3rd edn. McGraw-Hill, New York, p 392–419 Traxler P, Bold G, Buchdunger E et al 2001 Tyrosine kinase inhibitors: from rational design to clinical trials. Medical Research Reviews 21:499–512 Vail D, Kravis L, Cooley J et al 1997 Preclinical trial of doxorubicin entrapped in sterically stabilised liposomes in dogs with spontaneously arising malignant tumors. Cancer Chemotherapy and Pharmacology 39:410–416 Yoshida K, Watarai Y, Sakai Y et al 1998 The effect of intralesional bleomycin on canine acanthomatous epulis.

V. o. o. v. o. 1C Features of non-classic alkylating agents Drug Procarbazine (Matulane) Dacarbazine (DTIC) Mechanism of action Alkylation of DNA Exact mechanism is unknown but at least in part acts as an alkylating agent Metabolism Metabolised by the liver, excreted by the kidney as inactive metabolites Drug is eliminated by renal tubular secretion and extensively metabolized in the liver Principal toxicities Leucopenis and thrombocytopenia-late onset Myelosuppression, hepatotoxicity, anorexia, nausea, vomiting, alopecia, anaphylaxis Precautions Oral-capsules should not be divided Vesicant if extravasated.

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