By Wolfgang Haupt (auth.), Giuliano Colombetti, Francesco Lenci, Pill-Soon Song (eds.)

This ebook is predicated at the lectures given on the NATO complex examine Institute on "Sensory notion and Transduction in Aneural Organisms" held in Volterra (Pisa. Italy) from the 3rd to the fourteenth of September. 1984. The complicated research Institute was once deliberate as a excessive point path facing numerous features and difficulties of sensory belief and transduction of numerous environmental stimuli in aneural organisms. Scientists from diversified fields and cultural backgrounds have been current on the assembly. either as academics and as scholars. The lectures and the discussions that represented a good built-in interdisci­ plinary method of the questions thought of. on the finish of the complex learn Institute path. it used to be really transparent that. notwith­ status the plain heterogeneity of the subjects handled. unifying recommendations and concepts already existed, one of the most vital being the position of membranes and their physicochemical houses. All this could be mirrored within the content material of this ebook. We gratefully recognize the monetary sponsorship of the clinical Affairs department of NATO (Brussels), that made either the complex examine Institute on "Sensory notion and Transduction in Aneural Organisms" and this ebook attainable. ultimately. we're additionally indebted to Ms. Pat Parham Morgan who expertly retyped all of the chapters of the ebook and Ms. Leslie Schmidt of Plenum Publishing Co. supplied us important recommendation and recommendations at the instruction of this publication. G. Colombetti F. Lenci P. S.

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The consequence of effector binding would in this case be either a change in the degree of oligomerization of the external domain, or in the orientation of the external domains within the oligomer. By transmission of force through the membranespanning segment, this in turn would cause a change in degree of oligomerization, or orientation, of the cytoplasmic domains. There BIOCHEMISTRY OF SENSORY TRANSDUCTION IN BACTERIA 39 is some evidence for tetrameric MCP complexes (Che1sky and Dahlquist. 1980).

117:517-526. Parkinson, J. , 1976, cheA, cheB and cheC genes of Escherichia coli and their role in chemotaxis, ~. , 126:758-770. Parkinson, J. , 1980, Novel mutations affecting a signaling component for chemotaxis of Escherichia coli, J. , 142: 953-961. -- Parkinson, J. , 1981, Genetics of bacterial chemotaxis, in: Genetics as a Tool in Microbiology, S. W. Glover and D. A. , 31:265-290, Cambridge University Press, Cambridge. Parkinson, J. , and Hazelbauer, G. , 1983, Bacterial chemotaxis: Molecular genetics of sensory transduction and chemotactic gene expression, in: Gene Function in Prokaryotes, Cold Spring Harbor Laboratory, pp.

The impulse response for wild-type cells is shown in Fig. 3. 1 sec or shorter, while the response itself is relatively long, about 4 sec. The response is biphasic: it has two lobes of equal area. The positive lobe lasts about 1 sec, the negative lobe another 3 sec. 27 PHYSICS OF BACTERIAL CHEMOTAXIS 2 UJ (J) zC) a.. J •• ~~ -3 Fig. 4. ________ ~ __________-L__________ ~ ________ ~ LOG FRElJUENCY The Fourier transform of the impulse response for wild-type cells. A Bode plot--loglO (response amplitude) versus 10giO (stimulus frequency)--of the absolute magnitude of the complex Fourier transform of the impulse response shown in Fig.

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