By M. Schemann, D. Reiche, M. Neunlist (auth.), Priv.-Doz. Dr. M. K. Herbert, Professor Dr. P. Holzer, Professor Dr. N. Roewer (eds.)

After a protracted interval of forget, the gastrointestinal tract is more and more being recog­ nized as a big objective of anesthetics and anesthesia-related techniques, in addition to of stipulations and coverings relating to peri- and postoperative interval and inten­ sive care. medications utilized in anesthesia and in depth care and physiological or pathologi­ cal alterations within the perioperative interval have an effect on the digestive procedure in its functionality from the pharynx to the colon. lengthy postoperative ileus or stasis of propulsive peri­ stalsis within the seriously in poor health or multiply injured sufferer could impair enteral meals and provides upward push to problems resembling sepsis or a number of organ failure. In view of this new realizing of the medical relevance of intestine functionality, we felt booklet on difficulties of the gastrointestinal tract in anesthesia, the perioperative interval, and extensive care was once badly wanted. the current quantity is the manufactured from a world symposium which introduced jointly physiologists, pharmacologists, experimental and medical anesthetists, gastroenterologists, surgeons, and in depth care physicians to debate all significant modern points of bowel functionality in healthiness and below the impact of anesthesia, surgical procedure, and in depth care.

Show description

Read or Download Problems of the Gastrointestinal Tract in Anesthesia, the Perioperative Period, and Intensive Care: International Symposium in Würzburg, Germany, 1-3 October 1998 PDF

Similar international books

Mobile Information Systems II: IFIP International Working Conference on Mobile Information Systems, MOBIS 2005, Leeds, UK, December 6-7, 2005 (IFIP International Federation for Information Processing)

Cellular info structures II presents a suite of study at the making plans, research, layout, building, amendment, implementation, usage, assessment, and administration of cellular details platforms. The articles specialize in the consequences of this learn on the earth of trade, and deal with technical matters and constraints on cellular details structures functionalities and layout.

International Assessment of Research and Development in Simulation-Based Engineering and Science

Simulation-Based Engineering and technology (Sbe&S) cuts throughout disciplines, displaying super promise in parts from hurricane prediction and weather modeling to figuring out the mind and the habit of various different advanced structures. during this groundbreaking quantity, 9 distinct leaders examine the most recent examine developments, because of fifty two website visits in Europe and Asia and enormous quantities of hours of professional interviews, and speak about the results in their findings for the united states govt.

Interactive Theorem Proving: First International Conference, ITP 2010, Edinburgh, UK, July 11-14, 2010. Proceedings

This publication constitutes the refereed lawsuits of the 1st overseas convention on Interactive Theorem proving, ITP 2010, held in Edinburgh, united kingdom, in July 2010. The 33 revised complete papers provided have been rigorously reviewed and chosen from seventy four submissions. The papers are equipped in themes comparable to counterexample new release, hybrid method verification, translations from one formalism to a different, and cooperation among instruments.

Additional resources for Problems of the Gastrointestinal Tract in Anesthesia, the Perioperative Period, and Intensive Care: International Symposium in Würzburg, Germany, 1-3 October 1998

Example text

Erythromycin (Peeters 1993) has an effect similar to that of motilin and acts on motilin receptors. Although erythromycin has no effect on canine gastric strips in vitro, it accelerates gastric emptying in conscious dogs by inducing forceful gastric contractions. These strong contractions prevent the normal sieving function of the antropyloroduodenal region. The physiological relevance of this observation remains to be determined. In patients with severe gastroparesis, such as that seen in diabetic neuropathy, motilin and erythromycin are both effective in accelerating gastric emptying.

1997), is presumably mediated by [l-opioid receptors (Arzet et al. 1998b). Whether the lack of a b-receptormediated effect of DPDPE is species dependent or due to the absence of b-opioid receptors in the guinea-pig ileum remains open. Ketamine, another drug with potent analgesic properties, provides a good alternative to opioids under clinical conditions. The experiments concerning their effect on ileal motility revealed that racemic as well as the S( +) enantiomer of ketamine inhibited the intestinal reflex in a concentrationdependent manner, but about 1,000-fold concentrations of ketamine were required compared with fentanyl to completely abolish intestinal motility (Herbert et al.

1-100nM) brought about a concentration-dependent reduction of the pressure threshold to elicit a peristaltic wave and increased the frequency of contractions. With 100 nM cerulein the frequency of contractions was more than doubled over the entire observation period (Herbert et al. 1998c). Metoclopramide has either no effect or an inhibitory effect on peristalsis in the small intestine in vitro (Kuhn et al. 1998). J-M did not affect the pressure threshold or the frequency of contractions. J-M metoclopramide the peristalsis parameters remained unchanged in 5 of 10 segments, whereas in the other 5 segments the contractions were completely abolished (Kuhn et al.

Download PDF sample

Rated 4.44 of 5 – based on 42 votes