By Dante Cicchetti, Elaine F. Walker

Highlighting the significance of clinical development in knowing the neurodevelopmental origins of psychopathology, this research offers the paintings of a few of the main gifted researchers within the box. Its chapters illustrate the interactional strategies that represent the genesis and maturation of the mind. They show how constitutional vulnerability to psychological illness can come up from the interaction of a number of elements. Dante Cicchetti and Elaine Walker supply useful views for the pursuit of additional learn.

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Selecting Outcomes Most Likely Related to the Mechanism of Action of the Exposure Agent. This principle has been implicit in several earlier points and in some ways is obvious. However, outcome variables and timing of outcome measurement have varied widely in traditional neurobehavioral teratology studies in both human and animal models. Especially in human studies, scientific investigations often reflect cultural or Neurobehavioral Teratology 21 public biases regarding the harmful nature of the exposure.

1997). Cocaine use during pregnancy: Sensitive detection by hair assay. American Journal of Public Health 87, 352–358. Kosofsky, B. (1991). The effect of cocaine on developing human brain. National Institute Drug Abuse Monograph Series 114, 128–143. Kreek, M. J. (1996). Cocaine, dopamine, and the endogenous opioid system. Journal of Addictive Diseases 15, 73–96. Kristensen, J. , Ilett, K. , Hackett, L. , & Begg, E. J. (1999). Distribution and excretion of fluoxetine and norfluoxetine in human milk.

For attentional disorders), exposure to drugs in utero, and postnatal neglect define another cluster of effects that are both more generalizable than single effect, exposure models, and more biologically plausible. Similarly, the concepts of equifinality and multifinality are particularly important in considering the relation of environmental conditions (Cicchetti & Rogosch, 1999). Derived from general systems theory, these concepts capture the diversity of developmental pathways possible from a single event or associated with a particular presentation.

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