By J. M. Bennett (auth.), Prof. Dr. med. Franz Schmalzl, Dr. G. J. Mufti (eds.)

The myelodysplastic syndromes pose very important medical and medical demanding situations which in recent times have attracted turning out to be curiosity inside haemato-oncology and molecular genetics. Their strength as a version for the learn of human leukaemogenesis makes this some of the most intriguing fields in modern haematology.

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Applying these techniques, each cell of the peripheral blood and bone marrow can be examined with respect to different criteria, thus allowing the evaluation of extensive cytochemical patterns. The evaluation of cytochemically detectable anomalies was tested by four different cytologists, who examined the same smears. A high accordance was found.

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1985) Immune abnormalities in myelodysplastic syndromes. J Clin Pathol 38:908-911 30 T. J. Hamblin 22. Mufti OJ, Figes A, Hamblin TJ, Oscier DO, Copplestone JA (1986) Immunological abnormalities in mye\odysp\astic syndromes. 1. Serum immunoglobulins and autoantibodies. Br J Haematol 63:145-147 23. Kerndrup 0, Meyer K, Ellegaard J, Hockland P (1984) Natural killer (NK) cell activity and antibody-dependent cellular cytotoxicity (ADCC) in primary preleukaemic syndrome. Leuk Res 8:239-247 Pediatric Experiences in Myelodysplastic Syndrome * H.

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