By Erling Asmussen (auth.), Bengt Pernow, Bengt Saltin (eds.)

Howard G. Knuttgen of Biology, Boston collage, 2 Cummington division highway, Boston, 02215 Massachusetts, united states the connection of the formation of lactate acid to skeletal muscle strength free up in workout people was once first explored via A. V. Hill and colleagues (2l, 22). The time period "oxygen debt" was once recommended through them to explain the surplus oxygen intake of restoration which they felt was once heavily similar. a mix in their paintings and the sooner paintings of Krogh and Lindhard (35) re­ sulted at the moment within the trust specific amount of power liberate through the transition from leisure to workout was once supplied by way of a non-aerobic resource, glycolysis. The ensuing accumulation of lactic acid (as lactate) within the physique required an additional con­ sumption in the course of restoration for its oxidative elimination. Jervell (24) for that reason confirmed that, in workout, the best accumulation in blood happened in the course of the first couple of minutes. He felt that the blood lactate elevate was once as a result of a scarcity of oxygen in the course of the transition interval. The commentary was once additionally made for the 1st time that the elevated point of lac­ tate because of workout will be made to fall speedier if gentle workout was once hired via the topics in preference to sedentary restoration. The paintings of Margaria, Edwards and Dill (40) seemed in 1933. They saw that workout (treadmill working) should be carried on at low degrees with no major alterations in resting degrees of blood lactate.

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Extra info for Muscle Metabolism During Exercise: Proceedings of a Karolinska Institutet Symposium held in Stockholm, Sweden, September 6–9, 1970 Honorary guest: E Hohwu Christensen

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In such doubly innervated muscles stimulation of the soleus nerve caused the muscle to contract slowly, while stimulation of the FDL nerve elicited a fast contraction from the same muscle. Histochemically the muscle showed some areas with a population of fibers characteristic of soleus and other areas typical of' FDL. In normal muscles the fibers of different histochemical types were scattered among each other. In the cross-innervated and reinnervated muscles the fibers of the same histochemical type were arranged in small groups.

338 (1963) 854. 7. Z. 332 (1960) 328. 8. 15 (1969) 353. 9. Z. 331 (1959) 254. 10. Chem. 331 (1963) 180. 48 D. PETTE 11. Neurol. 11 (1964) 369. 12. , Dissertation,Faculty of Medicine, University of Munich 1967. 13. Biochem. 8 (1969) 273. 14. J. 94 (1965) 436. 15. J. 103 (1967) 391. 16. 110 (1962) 103. 17. ,11 (1964) 355. 18. Henneman,E. Neurophysiol. 28 (1965) 581. 19. Okayama 19(1965) 177. 20. R. Cytochem. 17 (1969) 828. 21. ,in preparation. 22. Nolte,J. ,and Pette,D. ,in "Recent Advances in Quantitative Histochemistry", Verlag Hans Huber,Bern,Stuttgart,in press.

II ( " • . , . , ... 1 t 1 , I ~ ' • , , . . ,..... '. -, \ , ~. • , . ' • J Fig. 4 Cross sections of normal FDL muscle of cat incubated for succinic dehydrogenase (A) and alkaline phosphatase (B). relationship between the oxidative metabolism and the capillary density of the muscle fibers (Fig. 5). However, a reinnervated nm)3cle differed from its normal counterpart in that the fibers of the same histochemical type occurred in small groups. The crossinnervated muscles showed a marked change in the oxidative enzymatic activity of the fibers.

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