By Edwin L Cooper
Basic Immunology offers a basic evaluation of the immune approach. It provides themes in immunology from all residing teams, treating cells, tissues, organs, and organismal degrees of organic association.
The publication includes 23 chapters equipped into 8 sections. part I serves as an creation to immunology-a technology, a comic strip of its background, a few of its newer individuals, whatever approximately amassing proof, immunology journals, and the whole biomedical firm of which immunology is simply an element. part II is dedicated to antigens whereas part III examines the immune approach in chordates and the ontogeny of the immune approach. part IV on cells of the immune method covers monocytes, macrophages, the 3 granulocytic kinds, and mast cells. part V bargains with phagocytosis and the interplay of lymphocytes. part VI is dedicated to antigens when it comes to antibody synthesis, antigen-antibody interactions, immunologlobulin constitution, and immunologlobulin meeting. part VII on organs of the immune process examines bone marrow, thymus, spleen, lymph nodes, and lymphoid aggregations. part VIII discusses the evolution of the immune process.
This textual content was once written for complex undergraduates. despite the fact that, its comprehensiveness makes it worthy to immunologists and biologists in any respect degrees in addition to scientific scholars and clinicians.
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Additional resources for General immunology
For example, it is accepted that when serum ofanimal X is injected into a rabbit the antibodies (precipitins) that have been induced should react strongly against the serum 41 from animal X . H owever, species specificity is often not absolute s ince it can be shown that kinship exists even between different species. C ross-reactions, due to shared an tigenic determinants, based on phylogenetic relationship, can be used as yet another means of classifying various species, as an alternative to con ventional methods of taxonomy.
Finally, on another level,functiona/ specificity can be defin ed, for example, in relation to certain seru m proteins such as the albumins, a globulins and i m munoglob ulins of a si ngle species; these proteins do not possess antigen ic specifities in common. In other words, these serum components are functionally different, but the albumins of rats and rabbits may contain common characteristics or determinants. KINDS OF ANTI GENS Natural BLOOD CELL ANTIGENS Numerous antigens are present not only in various whole organs and tissues, b ut also in the cells of tissues an d of blood.
Analysing the Immune System 25 p rotein components. A fter separation, an antibody to one or more of the components is p laced in association with them. L ines of precipitation form between the antigen (from the serum ) and the antibody. I mmunoelectrophoresis is a very sensitive procedure for clarifying antigens or antibodies in a mixture. Zone electrophoresis is performed in a supporting medium, while moving-boundary electrophoresis is carried out entirely in liquid phase (Figs. 4). 6. One supporting medium, polyacrylamide gel, provides a major advantage over zone electrophoresis in a starch block.