By J. E. Hall, G. A. Zampighi, Guido Zampighi, R. M. Davis

Hole junctions are found in approximately all tissues, despite their embryonic foundation and feature lengthy been of significant curiosity to scientists from many alternative disciplines. The foreign assembly on which this publication relies introduced jointly 157 scientists from 12 international locations and nearly as many medical disciplines. The papers offered on the assembly have been reviewed and up-to-date sooner than e-book during this publication. The seven elements of the publication growth from normal themes to the extra particular ones - the position of hole junctions in a number of tissues, rules and biochemistry, and melanoma

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USA 86, 5380-5384. , Rabadan-Diehl, C. and Dahl, G. (1991) Gating properties of connexin32 cell-cell channels and their mutants expressed in Xenopus oocytes. Proc. R. Soc. London Ser. Β 243, 5-11. ). E. Hall, G. A. M. ) Progress in Cell Research, Vol. V. , 1990). , 1990). , and, unexpectedly , in the liver (from 14 days post-coitum). This prompted us to further examine irnmunostaine d frozen sections of adult mouse and rat liver for the presenc e of Cx43 mRNA. Results Immunofluorescen t staining of adult rat and mouse liver sections indicate that the epitopes recognized by the antiCx43 site-directed antibodies are mainly localized in the hepatic parenchym a (Figs.

Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. L. and Goodenough, D . A (1989). Cloning and expression ofa Xenopus embryonic gap-junction protein. Science, 243, 1194-1195. , John, S. -P. (1991) Molecular cloning and characterization of a new member of the gap-junction gene family, connexin-31. J. Biol. Chem. 226, 6524-6531. H. W. (1988) Communication compartments in the gastrulating mouse embryo. J. Cell Biol. 107, 241-255.

Cell Biol. 105, 2621-2629. C. (1990) Molecular cloning and developmental expression of two chick embryo gap-junction proteins. J. Biol. Chem. 265, 14439-14443. G and Caveney, S. (1984). Separation of developmental compartments by a cell type with reduced junctional permeability. Nature (London) 309, 361-364. , Haeberli, P. and Smithies, O. (1984) A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. L. and Goodenough, D . A (1989). Cloning and expression ofa Xenopus embryonic gap-junction protein.

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