By C.G. Bernhard and J.P. Schadé (Eds.)

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Magnification as in (E). (A and B) Immature bipolar cells in superficial part of pyramidal layer. Better development in deeper part of layer, where pyramidal cells have basal dendrites. Apical dendrites terminate in deep part of marginal layer (La ma), mostly forming a few short branches (B). Precipitations obscure marginal zone in (A). Thin axons (ax) descend towards intermediate zone. (C) Collaterals from axons (ax) of deep pyramidal cell terminate in outer part of intermediate zone (La im), where stellate cells were seen in Fig.

As employed by Sidman et al. (1959). Such an analysis was not made in this investigation of the isocortex in the fetal sheep brain, and the following data are, therefore, only approximative. The migration of neuroblasts in the fetal sheep starts before the 1-g stage (estimated fetal age 20 days) and continues up to at least the 100-g level (estimated age 65 days). Except for the radiating fibers and rare epithelial cells the intermediate and cortical layers contain only neuroblasts and their derivatives up to the 40-g stage.

Large spaces between cells and radiating fibers. Palmgren’s method, x 480. C O R T I C A L D E V E L O P M E N T I N FETAL SHEEP 27 Fig. 13. 39-gram fetus, estimated age 57 days. Cresyl violet. (A) Detail of Fig. 11. Surface of hemispherical wall at top. Outer part of matrix (Mx) at bottom. Groups of cells separated by callosal and projection fibers in inner part of intermediate layer (La imi). Incipient stratification in pyramidal layer (La py) is due to formation of thin light band in middle part of layer, x 65.

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