By W. H. Utian, D. Serr (auth.), P. A. van Keep, R. B. Greenblatt, M. Albeaux-Fernet (eds.)

This publication encompasses a consensus on menopause examine, a consensus reached in the course of the First foreign Congress at the Menopause in June, 1976. The Congress introduced jointly approximately a hundred sixty five humans, such a lot of whom are engaged in learn during this box, within the hotel city of los angeles Grande Motte, close to Montpellier, France. It was once deliberate in order that the most emphasis will be at the trade of knowledge in small Workshop periods. Workshop Chairmen have been requested to provide summaries in their deliberations on the ultimate consultation. it truly is those summaries that shape the essence of this article. The Congress additionally incorporated six unfastened Communications classes. they're represented during this e-book by means of a small variety of papers revealed in complete (selected from a few forty contributions in all) that during the opinion of the editors, include facts that relatively supplement the Workshop summaries. All different papers are pointed out in those seasoned­ ceedings by way of titles and by way of the identify, association and tackle of the 1st writer. Organizing this Congress used to be a stimulating and heart-warming event. It used to be performed via the workers of the overseas well-being starting place in Brussels and Geneva, lower than the thoughtful auspices of the yank Geriatric Society and the clinical college of the collage of Montpellier. we're deeply thankful to those bodies.

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Extra info for Consensus on Menopause Research: A Summary of International Opinion The Proceedings of the First International Congress on the Menopause held at La Grande Motte, France, in June, 1976, under the auspices of The American Geriatric Society and The Medical F

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The evidence against estrone, however, is suspected to be insufficient to justify such preferences. THE ESTROGEN DEFICIENCY SYNDROME 41 Estrogen administration should preferably be cyclic in order to give the target organs, the endometrium and breast, I week of 'rest'. The treatment schedule should imitate the normal cyclic events as much as possible. In some cases climacteric complaints might reappear during the week in which no treatment is given. Therefore it was thought reasonable to continue with low doses during this period, since even during a normal cycle estrogen production continues at a reduced level.

Estrogen and Growth Hormone, Insulin Secretion and Blood Glucose Five years after menopause, glucose and serum immuno-reactive NON-GENITAL TARGET TISSUES 35 insulin (IRI) response to tolbutamide are not impaired. Hence menopause does not cause disturbance of carbohydrate metabolism in women without a disposition to diabetes. Even obese women showed a normal glucose and IRI-response. Moreover, 3-7 years' administration of natural estrogens in the post-menopause has no diabetogenic effect in obese or non-obese women.

Estrogen therapy should not be considered without the consent and full co-operation of the patient, and no patient should be persuaded to undergo it. Once begun, the patient should be kept informed of all aspects of the treatment. Atrophic changes of the vulva, vagina, urethra and bladder, or signs of beginning osteoporosis, are clear indications for estrogen therapy. There is, however, a strong point to be made for prophylactic treatment. It seems logical to prevent the symptoms of the deficiency syndrome rather than to treat them when they occur.

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