By Jr. Wayland J. Hayes

Instruction manual of Pesticide Toxicology, quantity three: sessions of insecticides specializes in the houses, toxicity, periods, and reactions of insecticides. the choice first bargains details on carbamate pesticides, nitro compounds and comparable phenolic insecticides, and artificial natural rodenticides. Discussions specialise in miscellaneous man made natural rodenticides, fluoroacetic acid and its derivatives, mononitrophenols, dinitrophenols, type of carbamates, and toxicology of anticholinesterase carbamates. The e-book then examines herbicides and fungicides and comparable compounds. subject matters contain nitrogen heterocyclic fungicides now not in a different way labeled, hydrazines, hydrozones, and diazo fungicides, anilino and nitrobenzenoid fungicides, antibiotics and botanicals, natural phosphorus herbicides, carbamate herbicides, and herbicidal oils and easy aliphatics. The booklet elaborates on miscellaneous insecticides, together with repellents, man made molluscicides, inhibitors of chitin synthesis, chemosterilants, and artificial acaricides. the choice is a worthwhile resource of information for researchers drawn to pesticide toxicology.

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1982; FMC, 1986b). 14 Rats given [ C]carbosulfan excreted 6 5 - 8 0 % of the dose in respired air, urine, and feces within 24 hr; elimination was nearly quantitative after 4 days. In 96 hr, urinary excretion was about 90% for ring-labeled, 5 3 % for DBA-labeled, and 35% for carbonyl-labeled carbosulfan. , 1982; FAO/WHO, 1985b; FMC, 1986b). Goats given two daily oral doses of ring-labeled carbosulfan for 7 days eliminated 80% of the dose in the urine, 2 - 3 % in the 1 4 feces, about 2% as respired C 0 2 , and less than 1 % in the milk.

1975). , 1975); the difference most likely depended on dosage. 1 mg/hr. , 1982). 28 μg/liter. 08% of a toxic dose per hour. , 1982). , 1984). , 1979). In reexamining the sperm samples from this study and comparing them against a new control group of 34 nonexposed workers in the same plant, Wyrobek etal. (1981) reported morphological abnormalities in the sperm from the exposed workers, not related to estimated exposure levels. Another evaluation of these same sperm samples showed no differences in sperm count or morphology between the exposed and control groups (MacLeod, 1982).

3 % of the administered radioactivity was found in rat fetuses. Levels were highest in fetal liver (Declume and Derache, 1976, 1977; Declume and Benard, 1977, 1978). , 1983). Radioac- 1149 tivity from carbaryl administered orally at parturition increased in the mammary gland and the neonates throughout the 48 hr after administration (Benard and Declume, 1979). Excretion of carbaryl differed qualitatively and quantitatively between pregnant and nonpregnant rats and mice, probably as a result of the pharmacodynamics of metabolism in another compartment (the fetus) following acute administration (Wheeler and Strother, 1974a; Strother and Wheeler, 1980).

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