By S. Fidone, C. Gonzales, B. Dinger, L. Stensaas (auth.), Helmut Acker, Andrzej Trzebski, Ronan G. O’Regan (eds.)

This quantity files the papers provided in Warsaw at the assembly of the foreign Society of Arterial Chemoreception (LS. A. C. ) prepared as a satellite tv for pc Symposium of the XXXI overseas Congress of the Union of Physiological Sciences (I. U. P. S. ) in Helsinki in July 1989. it's a 30 years previous culture to carry periodically foreign conferences on fresh advancements in chemoreceptor learn and to switch details among these folks attracted to chemoreception. the 1st assembly used to be geared up through B. B. Lloyd in Oxford in 1959. afterward, comparable overseas conferences have been held at abnormal durations. In 1966, R. W. Torrance prepared the second one assembly back in Oxford. In 1973, the 3rd assembly used to be prepared in Bristol (U. okay. ) through M. J. Purves. In 1974, a fourth assembly mixed with the XXVI I. U. P. S. Congress in Delhi was once prepared via A. S. Paintal in Srinagar (Kashmir, India). In 1976, H. Acker prepared the 5th assembly in Dortmund (F. R. G. ), and in 1979, C. Belmonte in Valla­ dolid (Spain) equipped the 6th foreign assembly commemorating the fiftieth anniversary of Fernando de Castro publishing his classical paintings at the constitution and attainable functionality of the carotid physique. In 1982, the 7th assembly was once as a result of D. J. Pallot in Leicester (U. ok. ), in 1985 - the 8th one as a result of A. J.

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W. Meech and N. B. Standen, Potassium activation in Helix aspersa neurones under voltage clamp: a component mediated by calcium influx, J. Physio!. 249:211 (1978). A. K. Ritchie, Two distinct calcium-activated potassium currents in a rat anterior pituitary cell line, J. Physiol. 385:591 (1987). B. , Sunderland, Massachusetts (1984). R. J. Miller, Multiple calcium channels and neuronal function, Science 235:46 (1987). J. Lopez-Lopez, C. Gonzalez, J. urena, and J. Lopez-Barneo, Low p02 selectively inhibits K channel activity in chemoreceptor cells of the mammalian carotid body, J.

5. 6. 40 C. Belmonte and C. Gonzalez, Mechanisms of chemoreception in the carotid body: possible models, in: "Physiology of the Peripheral Arterial Chemoreceptors," H. Acker and R. G. , Elsevier, Amsterdam (1983). C. Gonzalez, A. Obeso, A. Gomez-Nino, B. Dinger, and S. Fidone, Biogenic amine and neuropeptide transmitters in carotid body chemotransmission: experimental findings and perspectives, J. Appl. Physiol. (in press) • A. D. Thesis, Valladolid, Spain (1984). A. Obeso, S. Fidone, and C. Gonzalez, Pathways for calcium entry into type I cells: significance for the secretory response, in: "Chernereceptors in Respiratory Control," J.

Time course Table 1. Change of carotid chemoreceptor activityt in response to perfusions with KRB or KRB containing calcium channel blockers (100 ,lIM). 05 31 Time course of perfusion with three different calcium channel blockers and the recoveries after perfusion are summarized in Table 1. Compared to control values, chemoreceptor activity during perfusions of KRB containing calcium channel blockers was significantly depressed, an effect lasting into the post-perfusion period. Values of pH, Pe02' and Po2 for blood and perfusate for the control perfusions were not significantly different from the blocker-containing perfusions in each of the three sets of experiments (Table 2).

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