By Christoph Scholtissek, B.M. Richards, R. Vendrely, C. Vendrely, D.P. Bloch
The box of nucleic acids has grown to any such tremendeous dimension that it really is very unlikely to incorporate all guides about the chemistry and organic position of nucleic acids in an editorial of the size offered during this "Volume. accordingly, it is important to pick an important contributions and people no longer integrated "in recognized experiences. in lots of situations reference is made in basic terms to the authors who summarized their really good box in chapters of the 3 volumes of "The Nucleic Acids" (edB. E. CHARGAFF and J. N. DAVIDSON, Acad. Press, long island 1955 and 19(0) or to the "Nucleic Acid Outlines" (V. R. POTTER, Burgess Publishing Comp. Minneapolis), the place additional literature and extra targeted discussions will be stumbled on. evidence and theories might be handled, yet now not lists of references. as a result it's not attainable to stick to in all circumstances the historic improvement of an concept and to admowledge all courses that may be very important and inter esting from one other perspective. little or no is pointed out approximately tools within the box of nucleic acids.
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Extra info for Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins
1963), GIERER (1963), and SPYRIDE, and LIPMANN (1962) have found complexes between messenger RNA's and several ribosomes in animal and bacterial cells (polysomes or ergosomes), which were the only structures for the incorporation of amino acids in an in vi t r 0 system. Similar complexes were found wi,th poliovirus RNA (PENMAN et al. 19(3). Although in thymus nuclei an RNA fr,action has been found with a base composition corresponding to the cell DNA (SIBATANI et al. 19(2), from the theoretical standpoint one should not expect 'such a correspondence in diff'erentiated cells with different functions of an organism.
16 b. 109-115. - - 1964: Behavior of virus-spezific activities in tissue cultures infected with myxoviruses after chemical changes of the viral ribonucleic acid. Virology 22, 169--176. - - P. HAUSEN, H. HAUSEN, and W. ScHAFER, 1%2: Comparative studies of RNA and protein synthesis with a myxovirus and a small polyhedral virus. Cold Spring Harbor Symp. Quant. BioI. 27, 245-257. J. H. SCHNEIDER, and V.
Un 19(0). This enzyme has been used in studies of sequence analysis (HERBERT et al. 1962 h) of transfer RNA. RNases of other specificities and properties have been isolated from several sources. For reviews see G. SCHMIDT (1955) and HEPPEL and RABINOWITZ (1958). b) Deoxyribonueleases Two different kinds of DNases were found in nature. mono· and oligonucleotides. The second one (DNase II) has an acid pH-optimum and does not require divalent cations; 3'·mono- and oligonucleotides are formed. Both enzymes do not distinguish in general between pyrimidine and purine bases.