By Alex Gough

Here's a finished connection with all of the illnesses and issues of canine and cats which are both inherited or extra ordinary in yes breeds. there isn't any different unmarried publication that covers this topic. info on breed-related ailments from various top of the range assets are accrued jointly in a single position for the 1st time. while you are a veterinary health care professional or scholar wanting a convenient reference e-book, or a breeder desirous to comprehend extra approximately your individual breed then this booklet could be precious.

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Additional resources for Breed Predispositions to Disease in Dogs and Cats

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5 • Females predisposed • Mode of inheritance is polygenic Dermatological conditions Congenital hypotrichosis • Present at birth or develops in the first month of life • Predisposition for males suggests sex linkage Haematological/immunological conditions Haemophilia B • Factor IX deficiency • Also known as Christmas disease • Inherited as a sex-linked trait • Less common than haemophilia A Neurological conditions Shaker dog disease • Has been reported • Age of onset: 9 months to 2 years Atlantoaxial subluxation • Congenital • Age of onset: <1 year Ocular conditions Entropion (usually medial lower lids) • Breed predisposition; polygenic inheritance likely Figure 2a Although not listed as a predisposed breed, the Bichon Frise may be commonly affected by intervertebral disc disease.

5 • Females predisposed • Mode of inheritance is polygenic Dermatological conditions Congenital hypotrichosis • Present at birth or develops in the first month of life • Predisposition for males suggests sex linkage Haematological/immunological conditions Haemophilia B • Factor IX deficiency • Also known as Christmas disease • Inherited as a sex-linked trait • Less common than haemophilia A Neurological conditions Shaker dog disease • Has been reported • Age of onset: 9 months to 2 years Atlantoaxial subluxation • Congenital • Age of onset: <1 year Ocular conditions Entropion (usually medial lower lids) • Breed predisposition; polygenic inheritance likely Figure 2a Although not listed as a predisposed breed, the Bichon Frise may be commonly affected by intervertebral disc disease.

Hepatic cysts have not been seen in these cases Haematological conditions Pyruvate kinase deficiency • Inherited as an autosomal recessive trait Familial renal disease • Autosomal dominant inheritance • The condition is believed to be a glomerular basement-membrane disorder • Proteinuria may be an early indicator with cases progressing to renal failure at 1–8 years of age Musculoskeletal conditions Craniomandibular osteopathy • Aetiology unknown in this breed • Usually affects dogs aged 3–8 months CAIRN TERRIER Dermatological conditions Atopy • Common • May be more prevalent in females Endocrine conditions Diabetes mellitus • Possible breed predisposition • Usual age range: 4 –14 years; peak incidence: 7–9 years • Old, entire females are predisposed Gastrointestinal conditions Congenital bronchoesophageal fistula • Possible breed predisposition Congenital portosystemic shunt • Possible breed predisposition • Clinical signs usually seen in young dogs <1 year Microvascular portal dysplasia • Breed predisposition • Possibly inherited as a polygenic trait • May be asymptomatic Haemophilia B • Factor IX deficiency • Also known as Christmas disease • Inherited as a sex-linked trait • Less common than haemophilia A Inguinal hernia Neurological conditions Lysosomal storage disease – globoid cell leukodystrophy (Krabbe’s disease) • Autosomal recessive inheritance • Rare • Signs seen at 6–12 months Ocular conditions Refractory corneal ulceration • Breed predisposition • Usually middle-aged Ocular melanosis • Familial • Age of onset: 7–13 years • Predisposes to glaucoma • Schedule 3 of the BVA/KC/ISDS Eye Scheme Lens luxation • Autosomal dominant inheritance has been suggested • Age of onset: 4 –5 years Cataract • Inheritance suspected DOGS 43 Dogs 44 DOGS Retinal dysplasia • Mode of inheritance unknown, but autosomal recessive suspected Renal and urinary conditions Polycystic kidney disease • Autosomal recessive inheritance suggested • Cysts are found throughout the liver and kidneys from an early age (6 weeks).

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