By James Womack
The genetic info being unlocked via advances in genomic and excessive throughput applied sciences is speedily revolutionizing our realizing of developmental approaches in bovine species. this knowledge is permitting researchers unheard of perception into the genetic foundation of key features. Bovine Genomics is the 1st publication to collect and synthesize the data discovered during the bovine genome sequencing undertaking and view its sensible program to livestock and dairy creation.
Bovine Genomics opens with foundational chapters at the domestication of livestock and standard Mendelian genetics. construction on those chapters, insurance swiftly strikes to quantitative genetics and the advances of complete genome applied sciences. major assurance is given to such subject matters as epigenetics, mapping quantitative path loci, genome-wide organization reviews and genomic choice in livestock breeding. The publication is a precious synthesis of the sphere written by way of a world staff of top researchers.
Providing wide-ranging assurance of the subject, Bovine Genomic, is a vital advisor to the sector. the fundamental and utilized technology could be of use to researchers, breeders, and complex students.
Chapter 1 The Origins of farm animals (pages 1–10): Matthew D. Teasdale and Daniel G. Bradley
Chapter 2 Mendelian Inheritance in livestock (pages 11–19): Frank W. Nicholas
Chapter three Genetics of Coat colour in farm animals (pages 20–33): Sheila M. Schmutz
Chapter four From Quantitative Genetics to Quantitative Genomics: a private Odyssey (pages 34–50): Morris Soller
Chapter five Cartography of the Bovine Genome (pages 51–62): James E. Womack
Chapter 6 heritage of Linkage Mapping the Bovine Genome (pages 63–74): Stephanie D. McKay and Robert D. Schnabel
Chapter 7 Bovine X and Y Chromosomes (pages 75–100): F. Abel Ponce de Leon and Wansheng Liu
Chapter eight livestock Comparative Genomics and Chromosomal Evolution (pages 101–108): Denis M. Larkin
Chapter nine Sequencing the Bovine Genome (pages 109–122): Kim C. Worley and Richard A. Gibbs
Chapter 10 Bovine Genome structure (pages 123–143): David L. Adelson
Chapter eleven Bovine Epigenetics and Epigenomics (pages 144–168): Xiuchun (cindy) Tian
Chapter 12 Mapping Quantitative Trait Loci (pages 169–191): Joel I. Weller
Chapter thirteen Genome?Wide organization reports and Linkage Disequilibrium in farm animals (pages 192–210): M. E. Goddard and B. J. Hayes
Chapter 14 Genomic choice in pork farm animals (pages 211–233): Jeremy F. Taylor, Stephanie D. McKay, Megan M. Rolf, Holly R. Ramey, Jared E. Decker and Robert D. Schnabel
Chapter 15 effect of High?Throughput Genotyping and Sequencing at the id of Genes and editions Underlying Phenotypic edition in household livestock (pages 234–258): Michel Georges
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Additional resources for Bovine Genomics
1994) Black-ear gene and blood polymorphism in four southern Chinese cattle groups. Animal Genetics 25(Suppl 1): 89–90. , Schalles, R. (1984) Oculocutaneous hypopigmentation of Angus cattle. Bovine Practitioner 19: 92–99. M. (2009) Characterization of pro-opiomelanocortin gene variants and their effect on carcass traits in beef cattle. Sc. Thesis. University of Saskatchewan, Saskatoon, SK, Canada. L. M. (2010) The variant red coat colour phenotype of Holstein Cattle Maps to BTA27. Animal Genetics 41: 109–112.
64G>A mutation that has previously been reported in Charolais cattle (Oulmouden et al. 2005) and found a correlation with the shade of coat color. However, this mutation did not explain the total variation in shade observed. Further study indicated that additional splice variants of PMEL occurred in skin and other tissues (K¨ uhn and Weikard 2007b). A similar F2 and Backcross study was conducted by Guti´errez-Gil et al. 64G>A mutation, acting in a codominant fashion, ﬁt with the coat color in 93% of the cattle.
TYR The tyrosinase gene (TYR) is the primary gene causing complete albinism in many species of animals. Albino cattle have been reported in many breeds including Shorthorn (Greene et al. 1973), Braunvieh (Winzenried and Lauvergne 1970), Guernsey (Leipold et al. 1968), Holstein (Petersen et al. 1944), and Austrian Murboden (Schleger 1959). An insertion of a cytosine at position 926 of the TYR mRNA sequence causes a frameshift mutation leading to a premature stop codon at residue 316 in Brown Swiss or Braunvieh cattle (GenBank AY162287) (Schmutz et al.