By Oscar Sudilovsky (auth.), Oscar Sudilovsky, Henry C. Pitot, Lance A. Liotta (eds.)

The function! of this convention was once to not outline the 2 components which are being sure, that may be a good nigh most unlikely proposition. fairly, its concentration was once to be aware of the mechanistic similarities among advertising and development. Are the components concerned in the barriers a continuum? Are those simultaneous approaches? Or are a few of the affected cells within the level of promoting while even as others have gone through irreversi­ ble adjustments tha. t place them within the degree of development? Or are those phases an identical factor, yet referred to as through varied names? To discover such strategies we assembled investigators with quite a few again­ grounds and requested them to in particular tackle those and different questions on "The Boundaries", in the context of the consultation to which they con­ tributed. The convention lasted and a part days, from Wednesday to Friday. there have been not less than 4 audio system in step with consultation with morning and after­ midday periods on a daily basis, other than on Friday whilst the assembly ended at midday. the 1st day, each one speaker had 25 mins to offer a place, through 5 mins of dialogue. on the finish of the consultation there have been forty or 50 mins of trade on the entire concerns tested. For the rest days, there have been 25 mins of presentation and quarter-hour of discussion.

Show description

Read or Download Boundaries between Promotion and Progression during Carcinogenesis PDF

Best nonfiction_8 books

Thermal Conductivity 20

The foreign Thermal Conductivity convention was once begun in 1961 with the initiative of Mr. Charles F. Lucks and grew out of the wishes of researchers within the box. The meetings have been held each year from 1961 to 1973 and feature been held biennially when you consider that 1975 whilst our middle for Informa­ tion and Numerical information research and Synthesis (CINDAS) of Purdue collage grew to become the everlasting Sponsor of the meetings.

New Methods for Polymer Synthesis

The artwork and technology of macromolecular structure relies on synthesis, research, processing, and review of actual houses of polymers. The starting to be specificity of accessible artificial tools and the expanding refinement of analytical and actual research are progressively supplying a deeper perception into structure-property relationships of polymers, upon which many purposes should be dependent.

Animal Mind — Human Mind: Report of the Dahlem Workshop on Animal Mind — Human Mind, Berlin 1981, March 22–27

The oleic acid on a stay and wriggling sister or mom and chorus from evicting her from our hive. yet does the ensue­ rence of unintelligent habit suffice to illustrate the full absence of psychological event less than any situations? Ethologists from a few far away galaxy may possibly simply parent ex­ amples of silly and maladaptive habit in our personal species.

Global Climate Change and Freshwater Ecosystems

Worldwide weather swap is a sure bet. The Earth's weather hasn't ever remained static for lengthy and the chance for human-accelerated weather switch within the close to destiny appears to be like most likely. Freshwater platforms are in detail attached to weather in numerous methods: they could impact worldwide atmospheric techniques affecting weather; they're delicate early symptoms of weather swap simply because they combine the atmospheric and terrestrial occasions happening of their catchments; and, in fact, they are going to be plagued by weather switch.

Additional info for Boundaries between Promotion and Progression during Carcinogenesis

Example text

The percent conversion of papillomas to carcinomas was calculated using the following formula: Percent Conversion = (Total Carcinomas/Total Papillomas) x 100. Since all papillomas were not evaluated histologically, the number of carcinomas (as well as the percent conversion) is a minimal estimate. HETEROGENEITY OF PAPILLOMAS Most of the benign lesions which develop as the result of DMBA initiation-TPA promotion protocols are papillomas. Initiation of papillomas is characterized by a one-hit dose-response patternS, and the papillomas formed in initiation-promotion experiments are monoclona1 9 • Thus, papillomas apparently result from the clonal expansion of individual initiated cells.

Scribner, B. McKnight, N. K. Mottet, Evidence for a new model of tumor progression from carcinogenesis and tumor promotion studies with 7-bromomethylbenz[a]anthracene, Cancer Res. 43:2034-2041 (1983). 11. A. L. Reddy, P. J. Fialkow, Influence of dose of initiator on two-stage skin carcinogenesis in BALB/c mice with cellular mosaicism, Carcinogenesis 9:751-754 (1988). 1. 38 12. H. Hennings, D. Devor, M. L. Wenk, T. J. Slaga, B. Former, N. H. Colburn, G. T. Bowden, K. Elgjo, and S. H. Yuspa, Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz[a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice, Cancer Res.

A. N. Raick, Cell proliferation and promoting action in skin carcinoenesis, Cancer Res. 34:920-926 (1974). A. J. P. Klein-Szanto, S. M. Major, and T. J. Slaga, Induction of dark keratinocytes by 12-0-tetradecanoylphorbol-13-acetate and mezerein as an indicator of tumor promoting efficiency, Carcinogenesis 1:399-406 (1980) . T. J. Slaga, Cellular and molecular mechanisms of tumour promotion, Cancer Surveys 2:595-612 (1983). J. J. Reiners and T. J. Slaga, Effects of tumor promoters on the rate and commitment to terminal differentiation of subpopulations of murine keratinocytes, Cell 32:247-255 (1983).

Download PDF sample

Rated 4.66 of 5 – based on 25 votes