By Steven J. Zaloga, Wojciech Luczak, Barry Beldam

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Zone

Translated via Charlotte Mandell

Francis Servain Mirkovic, a French-born Croat who has been operating for the French Intelligence prone for fifteen years, is touring through educate from Milan to Rome. He’s sporting a briefcase whose contents he’s promoting to a consultant from the Vatican; the briefcase features a wealth of knowledge in regards to the violent heritage of the Zone—the lands of the Mediterranean basin, Spain, Algeria, Lebanon, Italy, that experience develop into Mirkovic’s specialty.

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If the blood sample will not be analyzed immediately or will be sent to an outside laboratory, a blood smear should be prepared, within minutes if possible. This step will minimize the morphologic changes that occur with aging or storage of leukocytes. The air-dried blood smear should be stored at room temperature and protected from vermin and humidity until staining by the laboratory. Laboratory Evaluation of Leukocytes 35 9. How do nucleated erythrocytes affect the leukogram? Most cell-counting methodologies include nucleated red blood cells (nRBCs) as leukocytes and report a falsely increased leukocyte concentration.

Metamyelocytes are the granulocytic precursors of band neutrophils and occur infrequently in blood as part of a left shift. An indented or kidney-shaped nucleus distinguishes metamyelocytes from band neutrophils. The nuclear chromatin is less condensed and the cytoplasm more basophilic in metamyelocytes than in band and segmented neutrophils. 15. Why is a fibrinogen test included on the complete blood count of some animals? Horses and ruminants often develop inflammatory disease without a significant change in the leukogram.

The neutropenia is an acute but transient change often followed by neutrophilia, since endotoxin causes release of neutrophils from the marrow storage pool. 18. Why does severe neutropenia occur with parvoviral infection? Canine and feline parvoviruses target cells with a high mitotic rate, including hematopoietic precursors. The blood and marrow pools of segmented neutrophils are quickly depleted because of the short half-life of neutrophils and the lack of replenishment by impaired granulopoiesis.

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